In this chapter, I want to offer an overview of how/why Gilles Deleuze and Félix Guattari have been influential on posthumanist thought before looking at how posthumanism is increasingly operating as a framework through which to consider film (and the media more generally) and before, in turn, looking at how Deleuze and Guattari influence such posthumanist readings of film. Finally, I should like briefly to offer a reading of various films from 2013 to 2014 that feature Scarlett Johansson in order to draw out some of the seeming contradictions surrounding posthumanism, namely that posthumanism remains a very human (if not humanist) way of thinking and, perhaps, of being in, or, better, with, the world.