This chapter suggests some ways in which the notion of global assemblage can be deployed to enhance policy analyses of the knowledge economy and, by inference, other policy discourses. It also makes knowledge an "object of inquiry' identifying some of the key theories of knowledge that have fueled the knowledge economy policy discourse. In so doing it identifies some of the ideas that have led to the global privileging of (1) digitized, codified, quantified, applied and commodified knowledge – particularly techno-science, and (2) national innovation systems. Overall it shows how certain theories have been deployed in the service of hegemonic knowledge systems.